While Tweetdeck is a good tool for use with Twitter, I found it stops periodically due to API overload but Seesmic doesn't. With my limited time available to tweet, I need a client that will be responsive and not hold me back from accomplishing all I want to in a small amount of time.
Seesmic does that for me and not just for Twitter. The desktop version updates to Facebook and now it has added LinkedIn!
One place, one tool to manage your interactions with your network!
How cool is that?
Get Seesmic here: http://seesmic.com/seesmic_desktop/sd2/